Lagevrio - molnupiravir

Introducing Lagevrio, an oral treatment for COVID-19 in adults at risk of severe illness1


What is Lagevrio?

Lagevrio contains the active ingredient molnupiravir and is used to treat mild to moderate COVID-19 in adults who are at risk for progressing to severe COVID-19 and/or hospitalisation. Lagevrio may help you to stay out of hospital and feel better.1


When to take Lagevrio?

If your doctor has prescribed you Lagevrio, it should be taken as soon as possible and within 5 days of developing COVID-19 symptoms.2


The most common side effects of Lagevrio are:1
  • Diarrhea
  • Dizziness
  • Nausea

Other side effects may also occur rarely, and as with any prescription drug, some side effects may be serious. Ask your doctor or pharmacist for more information. Tell your doctor or pharmacist promptly about these or any other unusual symptoms.1


Allergic Reactions

Do not take Lagevrio if you are allergic to molnupiravir or any of the other ingredients. Allergic reactions can happen in people taking Lagevrio. Stop taking Lagevrio and call your doctor right away if you get any of these symptoms: hives, rapid heartbeat, trouble swallowing or breathing, swelling of the mouth, lips, or face, throat tightness, hoarseness, skin rash.1


Not recommended if pregnant or breastfeeding

Lagevrio is not recommended in pregnancy. Discuss the need for a pregnancy test with your doctor if you are of childbearing potential and sexually active. If you can become pregnant, you should use effective birth control while you are taking Lagevrio and for 4 days after the last dose of Lagevrio.1


If you are a male who is sexually active with a partner who could become pregnant, use a reliable method of contraception during treatment and for 3 months after the last dose of Lagevrio.1


Breastfeeding is not recommended during treatment and for 4 days after the last dose of Lagevrio.1

Information if you have been prescribed Lagevrio


How to take Lagevrio

Take Lagevrio exactly as your doctor tells you.1


Take 4 capsules of Lagevrio every 12 hours (for example, at 8 am and at 8 pm)1


Take Lagevrio for 5 days1
It is important that you complete the full 5 days of treatment with Lagevrio. Do not stop taking Lagevrio before you complete the full 5 days of treatment, even if you feel better.1


Take Lagevrio
with or without food
1

If you forget to take Lagevrio

It is important that you do not miss or skip doses of this medicine.1

What to do if you miss a dose:


If it has been less than 10 hours since the missed dose

Take it as soon as you remember


If it has been more than 10 hours since the missed dose

Skip the missed dose and take your dose at the next scheduled time


Do not double the dose of Lagevrio to make up for the missed dose. If you are not sure what to do, call your doctor or pharmacist.1

Know the risk factors for severe COVID-19:5

While older adults are at a greater risk of becoming severely ill from COVID-19, some medical conditions can put a person of any age at increased risk of severe COVID-19. Here are some of the risk factors to look out for. These are not the only conditions that can  increase your risk for severe illness. For more information, talk to your doctor.


Active cancer

Morbid obesity (BMI greater than 35)

Compromised immunity

Diabetes

Chronic kidney disease

Chronic lung disease

Serious heart conditions

High blood pressure

The information on this website should be discussed with your doctor and does not replace their advice.

Know how to get tested for COVID-19

You can get a COVID-19 test at a range of locations, including Community Testing Centres and GP practices. You can also order rapid antigen tests (RATs) online.


Know how to report your RAT results



References: 

  1. Lagevrio Consumer Medicine Information, www.medsafe.govt.nz/Consumers/CMI/l/lageviro.pdf 
  2. Lagevrio Data Sheet
  3. Pharmac. Pharmaceutical Schedule. Available at: https://schedule.pharmac.govt.nz/ScheduleOnline.php. Accessed on: 26 Apr 2022. 
  4. Ministry of Health. About COVID-19. Available at: https://www.health.govt.nz/covid-19-novel-coronavirus/covid-19-health-advice-public/about-covid-19 Accessed on  7 June
  5. Ministry of Health. COVID-19: Higher risk people. Available at: https://www.health.govt.nz/covid-19-novel-coronavirus/covid-19-information-specific-audiences/covid-19-higher-risk-people. Accessed on 7 June.